Opening Remarks

Genetics in prostate cancer: from hereditary risk to precision medicine

All Roads Lead to AR: The Androgen Receptor in Modern Prostate Cancer Care

Immunosuppressive and Prognostic Significance of MS4A4A-Positive Macrophages in Bladder Cancer

Single-Cell and Spatial Transcriptomics Reveal Metastatic Subtyping and Molecular Mechanisms of Pheochromocytoma

The VGF-MYH9-GSK3β-Wnt/β-Catenin Axis Promotes Prostate Cancer Progression by Reprogramming Glycolysis and the Immune Microenvironment

A clinically translatable super-inert near-infrared fluorescent dye for surgical navigation

Advancing Clinical Research in Diabetic Kidney Disease: Experience from the DYNAMO Study

Clinical Big Data and Artificial Intelligence-Based Integrated Diagnosis and Treatment for Prostate Cancer

AR-degrading peptide, a novel solution for prostate cancer

SIRT5-Mediated Desuccinylation of FASN Regulates Lipid Metabolic Reprogramming and Promotes Prostate Cancer Cell Proliferation

The DIS3–glycoRNA Axis Drives Early Tumor Immune Evasion by Remodeling DC–T Cell Immune Responses

VHL inhibits autophagy and tumor development by modulating ATG14 hydroxylation in a PHD1-dependent manner

SLC26A7+ Cancer-Associated Fibroblasts Promote Axitinib Resistance in Renal Cell Carcinoma via TET1 Lactylation Modification

Cytoskeletal Protein KRT14 Governs Cisplatin Resistance by Modulating eIF4H-Dependent ACOX2 Translation and Lipid Metabolism in Bladder Cancer

A Novel Natural Tumor-Suppressive Micropeptide Removes the TRIM25-Mediated Anti-Ferroptosis Barrier and Inhibits Bladder Cancer Progression

Environmental Pollutant DEHP Drives Castration-Resistant Prostate Cancer Progression via OTUB2-Mediated Deubiquitination of MDM2

TE-RPA: A Single-Tube Telomerase Extension-Recombinase Polymerase Amplification-Based Electrochemical Biosensor for Precise Diagnosis of Urothelial Carcinoma

Integrative spatial dissection of tumor microenvironment architecture in bladder cancer invasion

Epigenomic Analysis Reveals AR-Associated Enhancer RNAs Modulate LTF Transcription to Influence Ferroptosis in Prostate Cancer

Exosomal ST6GAL1 from Prostate Cancer Promotes Perineural Invasion by Regulating Neuronal NGF Secretion via the Integrin β1/FAK/ERK Signaling Axis

LncCAM6A Promotes Sunitinib Resistance in Renal Cell Carcinoma by Activating Pyrimidine Synthesis via RBM15-Mediated m6A Modification of NAGS

Single-Cell Glyco-LacNAc Multi-Omics-Based Development of a Draining Lymph Node-Derived T Cell Therapy for Bladder Cancer

The Non-Canonical Function of Claudin-1 Drives Prostate Cancer Lineage Plasticity and Chemotherapy Resistance by Alleviating Lethal Endoplasmic Reticulum Stress

Opening Remarks

Fasting-Mimicking Diet-Driven Taurocholic Acid Reduction Enhances Renal Cell Carcinoma Immunotherapy by Attenuating MDSC-Mediated Immunosuppression

Gut Microbiota Dysbiosis After Androgen Deprivation Promotes Castration-Resistant Prostate Cancer Progression via TMAO-Mediated Remodeling of SPP1⁺ Tumor-Associated Macrophages

Single-Cell Spatial Atlas Reveals Prostate Cancer Immune Microenvironment Heterogeneity and Identifies CCL18⁺ Macrophages as a Predictive Biomarker for Immunotherapy Response

Wearable Low-Intensity Ultrasound Drives Fibroblasts Toward an FGF10⁺ Phenotype to Promote Postoperative Urethral Remodeling

Exploring the Interrelationship Among Metabolic Syndrome, IGF-1, and Benign Prostatic Hyperplasia in a Sprague-Dawley Rat Model

Environmental Endocrine-Disrupting Chemical Exposure Promotes Prostate Cancer Progression by Regulating the Tumor Immune Microenvironment

Integrated CosMx Spatial Transcriptomics and FFPE Single-Nucleus RNA Sequencing Reveal Perineural Invasion-Associated Tumor Subpopulations and Castration-Resistant Features in Prostate Cancer

Break

Exercise Alleviates Benign Prostatic Hyperplasia via Synergistic Serotonylation and Lactylation

Cytoplasmic Translocation of SIRT5 Remodels Glycolytic Metabolic Flux to Promote Castration-Resistant Prostate Cancer: Mechanisms and Therapeutic Strategies

Multi-Omics Integration Reveals ZDHHC24 Drives Sunitinib Resistance in Clear Cell Renal Cell Carcinoma by Regulating Lipid Metabolism

YWHAG Promotes Bladder Cancer Progression by Competitively Inhibiting FBXL7-Mediated Ubiquitination of BCLAF1

HE Slide-Based Spatial Gene Expression Prediction Model Deciphers Spatial Transcriptomic Features and Clinical Significance in Bladder Cancer

Lactylation Atlas of Clear Cell Renal Cell Carcinoma Reveals Ferritin Lactylation Regulates Ferroptosis by Inhibiting Ubiquitin-Proteasome Degradation

Single-Cell Sequencing Reveals SERPINE1⁺ Tumor Cells Remodel a Treg-Enriched Microenvironment via the JAK2/STAT3/TGF-β Axis to Drive Neoadjuvant Immunotherapy Resistance in Renal Cell Carcinoma

UBTF Remodels the Androgen Receptor Chromatin Binding Landscape and Activates DNA Damage Repair Programs to Promote Prostate Cancer Progression

GATAD1 Downregulation in Adrenal DLPC Promotes Ectopic Calcification of Arteries and Renal Interstitium

YTHDF3 Facilitates Cytoskeletal Remodeling to Promote Mitochondrial Transfer and CD8⁺ T Cell Exhaustion in Prostate Cancer

Mechanotransduction-Translation Coupling Mediates Cavernous Fibroblast Phenotypic Switching: A New Perspective on Diabetic Erectile Dysfunction Pathogenesis

Application Value of ADAM19 in CTC EMT Subtyping and Prognostic Assessment for Renal Cell Carcinoma

Targeting AREG⁺ Dendritic Cells Alleviates Renal Fibrosis Induced by Ischemia-Reperfusion Injury

Therapeutic Effect and Preliminary Mechanisms of FAST Whole-Cell Tumor Vaccine Combined with SBRT in Renal Cell Carcinoma

Identification of CD276 Ligands and Receptors and Exploration of Their Biological Functions in Urological Tumors

Summary